WHITEPAPER

MolecularDB: VarSome’s Big Data

Learn how VarSome's proprietary technology MolecularDB ensures meticulous integration and harmonization of genomics's Big Data. 

  • What is MolecularDB
  • 70+ integrated resources
  • Flexible search engine
  • ACMG-based classification
big_data

Download Now!

MolecularDB: VarSome’s Big Data

Download Now!

MolecularDB

What is MolecularDB

MolecularDB is VarSome’s integration and harmonization engine for genomics Big Data. VarSome provides access through MolecularDB to over 70 public genomics-related data sets, plus contributions from a 250'000-strong global community.

 

70+ Integrated Resources

70+ integrated resources

ClinVar, dbSNP, gnomAD, HPO, Ensembl, RefSeq, CIViC, COSMIC, ICGC, Kaviar, UniProt variants, UniProt domains, ExAC CNVs, ExAC genes, BRAVO, and more. We keep adding new ones!

Flexible search engine

Flexible search engine

VarSome offers very versatile variant look up mechanisms. You can search VarSome by HGVS nomenclature (both on DNA and on protein
level), rsID, gene name, transcript symbol or genomic location.

VarSome's full-text search functions like other Internet search engines with one important difference: the search query returns entries only from the VarSome aggregated knowledge base, thus showing you the result relevant only for the genomics field.

ACMG-based classification

ACMG-based classification

Automated variant classification according to the guidelines of the American College of Medical Genetics and Genomics (ACMG). VarSome’s robust implementation of ACMG guidelines contains explanations for each ACMG rule, along with why it has been triggered, or why not.